Dott. Fabio Timeus: elenco pubblicazioni scientifiche
Sono stati inseriti solo i full papers, tralasciando gli abstracts a Congressi
– Noonan Syndrome and Acute Myeloid Leukemia in Adults: The Importance of a Correct Multidisciplinary Approach during Childhood.
Timeus F.
Acta Haematol. 2020;143(6):518-519. doi: 10.1159/000506388. Epub 2020 Mar 10. PMID: 32155617
– Congenital Hypopigmentary Disorders with Multiorgan Impairment: A Case Report and an Overview on Gray Hair Syndromes.
Gironi LC, Zottarelli F, Savoldi G, Notarangelo LD, Basso ME, Ferrero I, Timeus F, Fagioli F, Maiuri L, Colombo E, Savoia P. Medicina
(Kaunas). 2019 Mar 25;55(3):78. doi: 10.3390/medicina55030078. PMID: 30934652; PMCID: PMC6473230.
– Reduction of CFU-GM and circulating hematopoietic progenitors in a subgroup of children with chronic neutropenia associated with severe infections and delayed recovery.
Timeus F, Crescenzio N, Foglia L, Doria A, Stillitano MG, Garelli E, Mazzone R, Vivalda L, Vallero S, Ramenghi U, Saracco P.
PLoS One. 2019 Mar 14;14(3):e0213782. doi: 10.1371/journal.pone.0213782. PMID: 30870474; PMCID: PMC6417780.
– Hematopoietic stem cell transplantation in Niemann-Pick disease type B monitored
by chitotriosidase activity.
Quarello P, Spada M, Porta F, Vassallo E, Timeus F, Fagioli F.
Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26811. Epub 2017 Nov 1.
– A retrospective study of paroxysmal nocturnal hemoglobinuria in pediatric and adolescent patients.
Mercuri A, Farruggia P, Timeus F, Lombardi L, Onofrillo D, Putti MC, Pillon M, Cantarini ME, Corti P, Tridello G, De Bortoli M, Pegoraro A, Cesaro S.
Blood Cells Mol Dis. 2017 May;64:45-50.
– Paroxysmal nocturnal haemoglobinuria from the prespective of paediatric haematologists.
Timeus F, Crescenzio N, Foglia L, Doria A, Saracco P.
Curr Drug Targets. 2016 Apr 1.
– Diagnosis and management of acquired aplastic anemia in childhood. Guidelines from the Marrow Failure Study Group of the Pediatric Haemato-Oncology Italian Association (AIEOP).
Barone A, Lucarelli A, Onofrillo D, Verzegnassi F, Bonanomi S, Cesaro S, Fioredda F, Iori AP, Ladogana S, Locasciulli A, Longoni D, Lanciotti M, Macaluso A, Mandaglio R, Marra N, Martire B, Maruzzi M, Menna G, Notarangelo LD, Palazzi G, Pillon M, Ramenghi U, Russo G, Svahn J, Timeus F, Tucci F, Cugno C, Zecca M, Farruggia P, Dufour C, Saracco P; Marrow Failure Study Group of the Pediatric Haemato-Oncology Italian Association.
Blood Cells Mol Dis. 2015 Jun;55(1):40-7.
– Paroxysmal nocturnal hemoglobinuria clones in children with acquired aplastic anemia: a multicentre study.
Timeus F, Crescenzio N, Longoni D, Doria A, Foglia L, Pagliano S, Vallero S, Decimi V, Svahn J, Palumbo G, Ruggiero A, Martire B, Pillon M, Marra N, Dufour C, Ramenghi U, Saracco P.
PLoS One. 2014 Jul 9;9(7):e101948.
– Functional evaluation of circulating hematopoietic progenitors in Noonan syndrome.
Timeus F, Crescenzio N, Baldassarre G, Doria A, Vallero S, Foglia L, Pagliano S, Rossi C, Silengo MC, Ramenghi U, Fagioli F, Cordero di Montezemolo L, Ferrero GB.
Oncol Rep. 2013 Aug;30(2):553-9.
– The coagulopathy in sepsis: significance and implications for treatment.
Saracco P, Vitale P, Scolfaro C, Pollio B, Pagliarino M, Timeus F.
Pediatr Rep. 2011 Sep 30;3(4):e30.
– Transcriptional hallmarks of Noonan syndrome and Noonan-like syndrome with loose anagen hair.
Ferrero GB, Picco G, Baldassarre G, Flex E, Isella C, Cantarella D, Corà D, Chiesa N, Crescenzio N, Timeus F, Merla G, Mazzanti L, Zampino G, Rossi C, Silengo M, Tartaglia M, Medico E.
Hum Mutat. 2012 Apr;33(4):703-9.
– In vitro anti-neuroblastoma activity of saquinavir and its association with imatinib.
Timeus F, Crescenzio N, Doria A, Foglia L, Pagliano S, Ricotti E, Fagioli F, Tovo PA, Cordero di Montezemolo L.
Oncol Rep. 2012 Mar;27(3):734-40.
– Paroxysmal nocturnal haemoglobinuria clones in children with acquired aplastic anaemia: a prospective single centre study.
Timeus F, Crescenzio N, Lorenzati A, Doria A, Foglia L, Pagliano S, Quarello P, Ramenghi U, Saracco P.
Br J Haematol. 2010 Aug;150(4):483-5.
– Timeus F, Crescenzio N, Lorenzati A, Doria A, Foglia L, Pagliano S, Quarello P, Ramenghi U, Saracco P.
Paroxysmal nocturnal haemoglobinuria clones in children with acquired aplastic anaemia: a prospective single centre study.
Br J Haematol. 2010 Aug;150(4):483-5. Epub 2010 Apr 28. PubMed PMID: 20456361.
– Gaipa G, Bugarin C, Longoni D, Cesana S, Molteni C, Faini A, Timeus F, Zecca M, Biondi A.
Aberrant GM-CSF signal transduction pathway in juvenile myelomonocytic leukemia assayed by flow cytometric intracellular STAT5 phosphorylation measurement.
Leukemia. 2009 Apr;23(4):791-3. Epub 2008 Oct 2.
PubMed PMID: 18830265.
– Gunetti M, Ferrero I, Rustichelli D, Berger M, Gammaitoni L, Timeus F, Piacibello W, Aglietta M, Fagioli F.
Refreezing of cord blood hematopoietic stem cells for allogenic transplantation: in vitro and in vivo validation of a clinical phase I/II protocol in European and Italian Good Manufacturing Practice conditions.
Exp Hematol. 2008 Feb;36(2):235-43.
– Timeus F, Crescenzio N, Fandi A, Doria A, Foglia L, Cordero di Montezemolo L.
In vitro antiproliferative and antimigratory activity of dasatinib in neuroblastoma and Ewing sarcoma cell lines.
Oncol Rep. 2008 Feb;19(2):353-9.
– Zanini C, Giribaldi G, Mandili G, Carta F, Crescenzio N, Bisaro B, Doria A, Foglia L, di Montezemolo LC, Timeus F, Turrini F.
Inhibition of heat shock proteins (HSP) expression by quercetin and differential doxorubicin sensitization in neuroblastoma and Ewing’s sarcoma cell lines.
J Neurochem. 2007 Nov;103(4):1344-54. Epub 2007 Aug 6.
– Timeus F, Crescenzio N, Ricotti E, Doria A, Bertin D, Saglio G, Tovo PA.
The effects of saquinavir on imatinib-resistant chronic myelogenous leukemia cell lines.
Haematologica. 2006 May;91(5):711-2.
– Timeus F, Crescenzio N, Sanavio F, Fazio L, Doria A, Foglia L, Pignochino Y, Berger M, Piacibello W, Madon E, Cordero di Montezemolo L, Fagioli F.
Multilineage engraftment of refrozen cord blood hematopoietic progenitors in NOD/SCID mice.
Haematologica. 2006 Mar;91(3):369-72.
– Timeus F, Crescenzio N, Doria A, Foglia L, Linari A, Giaccone M, Pastore G, di Montezemolo LC, Ramenghi U, Saracco P.
Flow cytometric evaluation of circulating CD34+ cell counts and apoptotic rate in children with acquired aplastic anemia and myelodysplasia.
Exp Hematol. 2005 May;33(5):597-604.
– Te Kronnie G, Timeus F, Rinaldi A, Crescenzio N, Spinelli M, Rosolen A, Ricotti E, Basso G.
Imatinib mesylate (STI571) interference with growth of neuroectodermal tumour cell lines does not critically involve c-Kit inhibition.
Int J Mol Med. 2004 Sep;14(3):373-82.
– Timeus F, Crescenzio N, Saracco P, Doria A, Fazio L, Albiani R, Cordero Di Montezemolo L, Perugini L, Incarbone E.
Recovery of cord blood hematopoietic progenitors after successive freezing and thawing procedures.
Haematologica. 2003 Jan;88(1):74-9.
– Timeus F, Ricotti E, Crescenzio N, Garelli E, Doria A, Spinelli M, Ramenghi U, Basso G.
Flt-3 and its ligand are expressed in neural crest-derived tumors and promote survival and proliferation of their cell lines.
Lab Invest. 2001 Jul;81(7):1025-37.
– Strippoli P, Bagnara GP, Montanaro L, Timeus F, Ferreri AM, Rocchi P.
Retinoic acid modulates stem cell factor secretion by human neuroblastoma cell lines.
Anticancer Res. 2000 Nov-Dec;20(6B):4361-6.
– Timeus F, Crescenzio N, Saracco P, Leone L, Ponzio G, Ramenghi U.
Cell cycle analysis in the diagnosis of Fanconi’s anamia.
Haematologica 2000 85:431-432.
– Ramenghi U, Garelli E, Valtolina S, Campagnoli MF, Timeus F, Crescenzio N, Mair M, Varotto S, D’Avanzo M, Nobili B, Massolo F, Mori PG, Locatelli F, Gustavsson P, Dahl N, Dianzani I.
Diamond-Blackfan anaemia in the Italian population.
Br J Haematol. 1999 Mar;104(4):841-8.
– Basso G, Timeus F.
Cytofluorimetric analysis of CD34 cells.
Bone Marrow Transplant. 1998 Dec;22 Suppl 5:S17-20. Review.
– Timeus F, Crescenzio N, Marranca D, Dall’Aglio M, Fazio L, Di Marco M, Saracco P, Ricotti M, Gabutti V.
Cell adhesion molecules in cord blood hematopoietic progenitors.
Bone Marrow Transplant. 1998 Jul;22 Suppl 1:S61-2.
– Scagni P, Saracco P, Timeus F, Farinasso L, Dall’Aglio M, Bosa EM, Crescenzio N, Spinelli M, Basso G, Ramenghi U.
Use of recombinant granulocyte colony-stimulating factor in Fanconi’s anemia.
Haematologica. 1998 May;83(5):432-7.
– Timeus F, Crescenzio N, Basso G, Ramenghi U, Saracco P, Gabutti V.
Cell adhesion molecule expression in cord blood CD34+ cells.
Stem Cells. 1998;16(2):120-6.
– Dianzani I, Garelli E, Crescenzio N, Timeus F, Mori PG, Varotto S, Nobili B, Brandalise S, Olivieri NF, Gabutti V, Ramenghi U.
Diamond-Blackfan anemia: expansion of erythroid progenitors in vitro by IL-9, but exclusion of a significant pathogenetic role for the IL-9 gene and the hematopoietic gene cluster on chromosome 5q.
Exp Hematol. 1997 Nov;25(12):1270-7.
– Timeus F, Crescenzio N, Valle P, Pistamiglio P, Piglione M, Garelli E, Ricotti E, Rocchi P, Strippoli P, Cordero di Montezemolo L, Madon E, Ramenghi U, Basso G.
Stem cell factor suppresses apoptosis in neuroblastoma cell lines.
Exp Hematol. 1997 Nov;25(12):1253-60.
– Valle P, Timeus F, Piglione M, Rosso P, di Montezemolo LC, Crescenzio N, Marranca D, Ramenghi U.
Effect of different exposures to desferrioxamine on neuroblastoma cell lines.
Pediatr Hematol Oncol. 1995 Sep-Oct;12(5):439-46.
– Miniero R, Busca A, Roncarolo MG, Saitta M, Iavarone A, Timeus F, Biondi A, Amoroso A, Perugini L, Ciuti E, et al.
HLA-haploidentical umbilical cord blood stem cell transplantation in a child with advanced leukemia: clinical outcome and analysis of hematopoietic recovery.
Bone Marrow Transplant. 1995 Aug;16(2):229-40.
– Timeus F, Valle P, Crescenzio N, Ruggieri L, Rosso P, Pagliardi GL, Cordero
di Montezemolo L, Gabutti V, Ramenghi U.
Effect of desferrioxamine and hydroxypyridones on hemopoietic progenitors and neuroectodermal tumor cells.
Am J Hematol. 1994 Nov;47(3):183-8.
– Miniero R, Ramenghi U, Crescenzio N, Perugini L, Busca A, Vassallo E, Timeus F.
Umbilical cord blood stem cell transplantation.
Int J Artif Organs. 1993 Dec;16 Suppl 5:113-5.
– Bagnara GP, Bonsi L, Strippoli P, Ramenghi U, Timeus F, Bonifazi F, Bonafe M, Tonelli R, Bubola G, Brizzi MF, et al.
Production of interleukin 6, leukemia inhibitory factor and granulocyte-macrophage colony stimulating factor by peripheral blood mononuclear cells in Fanconi’s anemia.
Stem Cells. 1993 Jul;11 Suppl 2:137-43.
– Gabutti V, Timeus F, Ramenghi U, Crescenzio N, Marranca D, Miniero R, Cornaglia G, Bagnara GP.
Expansion of cord blood progenitors and use for hemopoietic reconstitution.
Stem Cells. 1993 Jul;11 Suppl 2:105-12.
– Gabutti V, Timeus F, Ramenghi U, Saracco P, Fassio D, Giubellino MC, Miniero R, Madon E.
Human cord blood progenitors: kinetics, regulation and their use for hemopoietic reconstitution.
Bone Marrow Transplant. 1993;12 Suppl 1:84-6.
– Bagnara GP, Strippoli P, Bonsi L, Brizzi MF, Avanzi GC, Timeus F, Ramenghi U, Piaggio G, Tong J, Podesta M, et al.
Effect of stem cell factor on colony growth from acquired and constitutional (Fanconi) aplastic anemia.
Blood. 1992 Jul 15;80(2):382-7.
– Bagnara GP, Zauli G, Vitale L, Rosito P, Vecchi V, Paolucci G, Avanzi GC,
Ramenghi U, Timeus F, Gabutti V.
In vitro growth and regulation of bone marrow enriched CD34+ hematopoietic progenitors in Diamond-Blackfan anemia.
Blood. 1991 Nov 1;78(9):2203-10.
– Ramenghi U, Saracco P, Timeus F, Bertoldi R, Miniero R.
Use of ascorbate for the treatment of refractory idiopathic thrombocytopenic purpura in children.
Am J Pediatr Hematol Oncol. 1991 Winter;13(4):486-7.
– Gabutti V, Piga A, Cordero A, Fortina P, Timeus F.
L’eritropoiesi nella talassemia.
Haematologica. 1981 66: 258-268.